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專利名稱(中)	用於評估病毒感染之一懷孕個體之妊娠風險的方法
專利名稱(英)	METHOD FOR EVALUATING PREGNANCY RISK OF A PREGNANT INDIVIDUAL INFECTED WITH A VIRUS
專利家族	中華民國：I907122
專利權人	國立清華大學 100.00%
發明人	鄭兆珉,沈靜茹,胡書瑜,楊博鈞,鄭美秀,洪俊傑
技術領域	生化醫藥

專利摘要(中)
本發明係關於一種用於評估病毒感染之一懷孕個體之妊娠風險的方法。該方法包含以下步驟：(a)取得病毒感染之該懷孕個體的一生物樣本；(b)檢測該生物樣本中至少一微小核醣核酸的表現量，其中該至少一微小核醣核酸係選自由hsa -miR-20a -5p、hsa-miR-20b-5p及hsa -miR-25-3p所組成之群組；以及(c)比對步驟(b)中各該至少一微小核醣核酸的表現量與一對照組之對應相同微小核醣核酸的表現量，其中當病毒感染之該懷孕個體之該至少一微小核醣核酸的表現量高於該對照組的表現量時，則評估該懷孕個體存在有妊娠風險。

專利摘要(中)

本發明係關於一種用於評估病毒感染之一懷孕個體之妊娠風險的方法。該方法包含以下步驟：(a)取得病毒感染之該懷孕個體的一生物樣本；(b)檢測該生物樣本中至少一微小核醣核酸的表現量，其中該至少一微小核醣核酸係選自由hsa -miR-20a -5p、hsa-miR-20b-5p及hsa -miR-25-3p所組成之群組；以及(c)比對步驟(b)中各該至少一微小核醣核酸的表現量與一對照組之對應相同微小核醣核酸的表現量，其中當病毒感染之該懷孕個體之該至少一微小核醣核酸的表現量高於該對照組的表現量時，則評估該懷孕個體存在有妊娠風險。

專利摘要(英)
The present invention relates to a method for evaluating pregnancy risk of a pregnant individual infected with a virus. The method comprises the following steps: (a) obtaining a plurality of biological samples from the virus-infected pregnant individual; (b) detecting the expression levels of at least one microRNA in the biological samples, wherein the at least one microRNA is selected from the group consisting of hsa -miR-20a -5p, hsa-miR-20b-5p, and hsa -miR-25-3p; and (c) comparing the expression levels of the at least one microRNA in step (b) with the corresponding expression levels of the same microRNA in a control group, wherein when the expression level of the at least one microRNA in the virus-infected pregnant individual is higher than that of the control group, the pregnancy risk is evaluated for the pregnant individual.

專利摘要(英)

The present invention relates to a method for evaluating pregnancy risk of a pregnant individual infected with a virus. The method comprises the following steps: (a) obtaining a plurality of biological samples from the virus-infected pregnant individual; (b) detecting the expression levels of at least one microRNA in the biological samples, wherein the at least one microRNA is selected from the group consisting of hsa -miR-20a -5p, hsa-miR-20b-5p, and hsa -miR-25-3p; and (c) comparing the expression levels of the at least one microRNA in step (b) with the corresponding expression levels of the same microRNA in a control group, wherein when the expression level of the at least one microRNA in the virus-infected pregnant individual is higher than that of the control group, the pregnancy risk is evaluated for the pregnant individual.

聯絡資訊
承辦人姓名	楊慧敏
承辦人電話	(03)571-5131 #31181
承辦人Email	hmyang@mx.nthu.edu.tw