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專利授權區
專利名稱(中)	用於去除全血中紅血球的晶片及方法
專利名稱(英)	CHIP AND METHOD FOR ISOLATING RED BLOOD CELL FROM WHOLE BLOOD
專利家族	中華民國：I827188 美國：US-2024-0042439-A1(公開號)
專利權人	國立清華大學 100.00%
發明人	曾繁根
技術領域	生化醫藥

專利摘要(中)
本實施例的一種用於去除全血中紅血球的晶片包括容置空間、多孔薄膜以及微流道系統。容置空間用以承載包括紅血球碎片的血液樣本。多孔薄膜位於容置空間的底部且包括多個貫孔，貫孔的孔徑大於紅血球碎片的尺寸且小於白血球與循環腫瘤細胞的平均直徑。微流道系統包括液體入口部、液體出口部以及微流道。微流道位於液體入口部及液體出口部之間且與液體入口部及液體出口部連通。微流道位於多孔薄膜下方，其中紅血球碎片穿過多孔薄膜而進入微流道。

專利摘要(中)

本實施例的一種用於去除全血中紅血球的晶片包括容置空間、多孔薄膜以及微流道系統。容置空間用以承載包括紅血球碎片的血液樣本。多孔薄膜位於容置空間的底部且包括多個貫孔，貫孔的孔徑大於紅血球碎片的尺寸且小於白血球與循環腫瘤細胞的平均直徑。微流道系統包括液體入口部、液體出口部以及微流道。微流道位於液體入口部及液體出口部之間且與液體入口部及液體出口部連通。微流道位於多孔薄膜下方，其中紅血球碎片穿過多孔薄膜而進入微流道。

專利摘要(英)
In an embodiment, a chip is used for isolating RBC from a whole blood and includes an accommodating space, a porous membrane and a microchannel system. The accommodating space is configured for containing a whole blood sample including RBC debris. The porous membrane is disposed at a bottom of the accommodating space and includes a plurality of pores. A diameter of the pores is larger than a size of the RBC debris and larger than a mean diameter of WBCs and CTCs. The microchannel system includes a liquid inlet, a liquid outlet and a microchannel. The microchannel is disposed between and communicates with the liquid inlet and the liquid outlet. The microchannel is disposed under the porous membrane.

專利摘要(英)

In an embodiment, a chip is used for isolating RBC from a whole blood and includes an accommodating space, a porous membrane and a microchannel system. The accommodating space is configured for containing a whole blood sample including RBC debris. The porous membrane is disposed at a bottom of the accommodating space and includes a plurality of pores. A diameter of the pores is larger than a size of the RBC debris and larger than a mean diameter of WBCs and CTCs. The microchannel system includes a liquid inlet, a liquid outlet and a microchannel. The microchannel is disposed between and communicates with the liquid inlet and the liquid outlet. The microchannel is disposed under the porous membrane.

聯絡資訊
承辦人姓名	楊美茹
承辦人電話	03-5715131 #62305
承辦人Email	mjyang2@mx.nthu.edu.tw