專利授權區國立清華大學國際產學營運總中心 Operations Center for Industry Collaboration

搜尋專利授權區

關鍵字

» 新增關鍵字

選單

專利授權區

專利授權區
專利名稱(中)	用以偵測膽管癌細胞的化合物與方法
專利名稱(英)	COMPOUNDS AND METHODS FOR DETECTING CHOLANGIO-CANCEROUS CELLS
專利家族	中華民國：I778596 美國：11,506,664
專利權人	中央研究院 51.00% ,國立清華大學 49.00%
發明人	李國賓,洪上程,普麗雅
技術領域	生化醫藥

專利摘要(中)
本揭示內容是關於一種用於偵測循環性癌細胞的新穎式(I)化合物，特別是用於偵測來自一生物學樣本中的膽管癌細胞，其中，R1及 R2個別是 H 或–SO3M；且 M 是一單價陽離子並選自由鈉離子、鉀離子、鋰離子及銨離子所組成的群組。本揭示內容亦揭示一種從一疑似罹患膽管癌(CCA)之個體的生物學樣本中用以偵測一膽管癌細胞的方法。該方法包含：使該生物學樣本與一預塗布(pre-coated)該式(I)化合物的磁珠接觸；在一免疫分析中，偵測由該磁珠與該生物學樣本所形成的一複合物；其中，該複合物的存在表示該個體罹患CCA。

專利摘要(中)

本揭示內容是關於一種用於偵測循環性癌細胞的新穎式(I)化合物，特別是用於偵測來自一生物學樣本中的膽管癌細胞，其中，R1及 R2個別是 H 或–SO3M；且 M 是一單價陽離子並選自由鈉離子、鉀離子、鋰離子及銨離子所組成的群組。本揭示內容亦揭示一種從一疑似罹患膽管癌(CCA)之個體的生物學樣本中用以偵測一膽管癌細胞的方法。該方法包含：使該生物學樣本與一預塗布(pre-coated)該式(I)化合物的磁珠接觸；在一免疫分析中，偵測由該磁珠與該生物學樣本所形成的一複合物；其中，該複合物的存在表示該個體罹患CCA。

專利摘要(英)
Disclosed herein is a novel compound of formula (I) for detecting circulating cancerous cells, particularly, cholangio-cancerous cells, from a biological sample, wherein, R 1and R 2are independently H, or –SO 3M; and M is a monovalent cation selected from the group consisting of sodium ion, potassium ion, lithium ion or ammonium ion. Also disclosed herein is a method of detecting cholangio-cancerous cells from a biological sample of a subject suspected of having cholangiocarcinoma (CCA). The method includes steps of, contacting the biological sample with a magnetic bead pre-coated with the compound of formula (I); detecting a complex formed between the magnetic bead and the biological sample in an immunoassay; wherein, the presence of the complex is an indication that the subject has CCA.

專利摘要(英)

Disclosed herein is a novel compound of formula (I) for detecting circulating cancerous cells, particularly, cholangio-cancerous cells, from a biological sample, wherein, R 1and R 2are independently H, or –SO 3M; and M is a monovalent cation selected from the group consisting of sodium ion, potassium ion, lithium ion or ammonium ion. Also disclosed herein is a method of detecting cholangio-cancerous cells from a biological sample of a subject suspected of having cholangiocarcinoma (CCA). The method includes steps of, contacting the biological sample with a magnetic bead pre-coated with the compound of formula (I); detecting a complex formed between the magnetic bead and the biological sample in an immunoassay; wherein, the presence of the complex is an indication that the subject has CCA.

聯絡資訊
承辦人姓名	楊慧敏
承辦人電話	(03)571-5131 #31181
承辦人Email	hmyang@mx.nthu.edu.tw