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專利授權區
專利名稱(中)	聚脯胺酸奈米籠狀化合物、其製備方法及其用途
專利名稱(英)	POLYPROLINE NANOCAGE COMPOUND, MANUFACTURING METHOD THEREOF AND USE THEREOF
專利家族	中華民國：I913917 美國：US-2026-0085133-A(公開號)
專利權人	國立清華大學 100.00%
發明人	王聖凱,蔡嘉龍,徐詣誠,邱筱玲,陳芓源
技術領域	光電光學

專利摘要(中)
本發明提供一種聚脯胺酸奈米籠狀化合物，其包含二環肽骨架以及至少三連接分子。每一個環肽骨架包含至少三聚脯胺酸螺旋桿以及至少三轉角分子，且至少三聚脯胺酸螺旋桿中之二者由至少三轉角分子中之一者連接形成一閉合環。至少三連接分子分別自二環肽骨架中之一者的每一個聚脯胺酸螺旋桿連接至二環肽骨架中之另一者的每一個聚脯胺酸螺旋桿。藉此，本發明之聚脯胺酸奈米籠狀化合物具有生物相容性，且可控制官能基的連接位置與數量，以適於各種應用層面。

專利摘要(中)

本發明提供一種聚脯胺酸奈米籠狀化合物，其包含二環肽骨架以及至少三連接分子。每一個環肽骨架包含至少三聚脯胺酸螺旋桿以及至少三轉角分子，且至少三聚脯胺酸螺旋桿中之二者由至少三轉角分子中之一者連接形成一閉合環。至少三連接分子分別自二環肽骨架中之一者的每一個聚脯胺酸螺旋桿連接至二環肽骨架中之另一者的每一個聚脯胺酸螺旋桿。藉此，本發明之聚脯胺酸奈米籠狀化合物具有生物相容性，且可控制官能基的連接位置與數量，以適於各種應用層面。

專利摘要(英)
The present disclosure provides a polyproline nanocage compound, which includes two cyclic peptide scaffolds and at least three connecting molecules. Each of the two cyclic peptide scaffolds includes at least three polyproline II helix rods and at least three turn-angle molecules, and two of the at least three polyproline II helix rods are connected by one of the at least three turn-angle molecules to form a closed ring. The at least three connecting molecules are connected from each of the polyproline II helix rods of one of the two cyclic peptide scaffolds to each of the polyproline II helix rods of another of the two cyclic peptide scaffolds. Accordingly, the polyproline nanocage compound of the present disclosure is biocompatible, and the connection position and the number of the functional groups can be controlled, which is suitable for the various applications.

專利摘要(英)

The present disclosure provides a polyproline nanocage compound, which includes two cyclic peptide scaffolds and at least three connecting molecules. Each of the two cyclic peptide scaffolds includes at least three polyproline II helix rods and at least three turn-angle molecules, and two of the at least three polyproline II helix rods are connected by one of the at least three turn-angle molecules to form a closed ring. The at least three connecting molecules are connected from each of the polyproline II helix rods of one of the two cyclic peptide scaffolds to each of the polyproline II helix rods of another of the two cyclic peptide scaffolds. Accordingly, the polyproline nanocage compound of the present disclosure is biocompatible, and the connection position and the number of the functional groups can be controlled, which is suitable for the various applications.

聯絡資訊
承辦人姓名	黃允恬
承辦人電話	(03)571-5131#62305
承辦人Email	yuntian@mx.nthu.edu.tw