A device and method for improving light penetration is provided and applied to human tissues for biophotonics technology. When a laser beam penetrates a tissue inside a human body for biophotonics technology, ultrasounds generated by a high intensity focused ultrasound (HIFU) probe are focused to form an acoustic vortex around a forward path of the laser beam, causing the laser beam to pass through a central silent vortex action region of the acoustic vortex. A virtual optical waveguide is formed on surrounding tissues in the forward path of the laser beam through the acoustic vortex, to increase fluence of the laser beam through the acoustic vortex, and improve light penetration of the laser beam. |