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專利名稱(中) 捕獲循環腫瘤癌細胞裝置、其方法以及循環腫瘤癌細胞捕獲暨藥物敏感性測試的方法
專利名稱(英) CIRCULATING TUMOR CELL CAPTURE DEVICE, METHOD THEREOF AND METHOD FOR CIRCULATING TUMOR CELL CAPTURE AND DRUG SENSITIVITY ANALYSIS
專利家族 中華民國:I719605
專利權人 國立清華大學 60% ,臺中榮民總醫院 40%
發明人 穆宣佑,黃振煌,蕭自宏
技術領域 材料化工,生化醫藥
專利摘要(中)
一種捕獲循環腫瘤癌細胞裝置,包含晶片系統以及幫浦。晶片系統包含匯流晶片與下層晶片組。下層晶片組設置於匯流晶片的下表面,並包含流道晶片、分流晶片以及多孔性膜。流道晶片設置於匯流晶片的下表面,分流晶片為可拆卸地疊設於流道晶片之下。多孔性膜嵌入設置於流道晶片內,檢體可通過多孔性膜於流道晶片與分流晶片間流動,並使循環腫瘤癌細胞捕獲於多孔性膜上。藉此,本發明之捕獲循環腫瘤癌細胞裝置可進行富集活的循環腫瘤癌細胞,或可直接原位進行藥物敏感性分析和染色分析,提供使用者快速且精準之分析循環腫瘤癌細胞方式。
專利摘要(英)
A circulating tumor cell capturing device includes a chip system and a pump. The chip system includes a confluence chip and lower chip set. The lower chip set is disposed on a lower surface of the confluence chip, and including a channel chip, a split chip, and a porous membrane. The channel chip is disposed on the lower surface of the confluence chip. The split chip is detachably disposed under the channel chip. The porous membrane is embedded disposed inside of the channel chip. The sample can flow between the channel chip and the split chip through the porous film, and the circulating tumor cell can be trap on the porous membrane. Therefore, it is favorable for enriching live circulating tumor cell or directly conducting in-situ analysis of drug resistance and staining analysis by the circulating tumor cell capturing system of the present disclosure so as to provide users with fast and accurate way of analyzing circulating tumor cell.
聯絡資訊
承辦人姓名 呂建潁
承辦人電話 03-5715131 #31061
承辦人Email chienying_lu@mx.nthu.edu.tw
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