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專利名稱(中)	乳癌風險評估方法
專利家族	中華民國：I866867
專利權人
發明人	朱麗安,黃兆寅,林佳蓉
技術領域	生化醫藥

專利摘要(中)
一種乳癌風險評估方法，利用一運算裝置來執行以下步驟：獲得一受測者的一組織切片的切片影像，該切片影像指示出該組織切片所含的多個細胞、多個目標染色體訊號及多個目標蛋白訊號；對於每一細胞，獲得位於該細胞內的一目標蛋白訊號數量、位於該細胞內的一目標染色體訊號數量及一訊號數量比；根據該等訊號數量比對該等細胞進行排序，以獲得N個關鍵細胞；及根據所有關鍵細胞的目標蛋白訊號數量及目標染色體訊號數量，獲得一指示出該受測者罹患乳癌的風險高低的評估結果。

專利摘要(中)

一種乳癌風險評估方法，利用一運算裝置來執行以下步驟：獲得一受測者的一組織切片的切片影像，該切片影像指示出該組織切片所含的多個細胞、多個目標染色體訊號及多個目標蛋白訊號；對於每一細胞，獲得位於該細胞內的一目標蛋白訊號數量、位於該細胞內的一目標染色體訊號數量及一訊號數量比；根據該等訊號數量比對該等細胞進行排序，以獲得N個關鍵細胞；及根據所有關鍵細胞的目標蛋白訊號數量及目標染色體訊號數量，獲得一指示出該受測者罹患乳癌的風險高低的評估結果。

專利摘要(英)
In a method of breast cancer risk assessment, a computing device is configured to perform the steps of: obtaining a slice image of a tissue slice of a subject, the slice image indicates multiple cells, multiple target chromosome signals, and multiple target protein signals contained in the tissue slice; for each cell, obtaining a target protein signal quantity located in the cell, a target chromosome signal quantity located in the cell, and a signal quantity ratio; sorting the cells according to the signal quantity ratio to obtain a number N of key cells; and obtaining an assessment result indicating the subject’s risk of breast cancer based on the target protein signal quantity and the target chromosome signal quantity of all key cells.

專利摘要(英)

In a method of breast cancer risk assessment, a computing device is configured to perform the steps of: obtaining a slice image of a tissue slice of a subject, the slice image indicates multiple cells, multiple target chromosome signals, and multiple target protein signals contained in the tissue slice; for each cell, obtaining a target protein signal quantity located in the cell, a target chromosome signal quantity located in the cell, and a signal quantity ratio; sorting the cells according to the signal quantity ratio to obtain a number N of key cells; and obtaining an assessment result indicating the subject’s risk of breast cancer based on the target protein signal quantity and the target chromosome signal quantity of all key cells.

聯絡資訊
承辦人姓名	楊美茹
承辦人電話	03-5715131 #62305
承辦人Email	mjyang2@mx.nthu.edu.tw