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專利授權區

專利授權區
專利名稱(中)	早期階段檢測肝癌及預測肝癌轉移之方法
專利名稱(英)	A METHOD FOR EARLY DIAGNOSIS OF LIVER CANCER AND PREDICTION OF METASTASIS
專利家族	中華民國：I440855 美國：8,628,920
專利權人	國立清華大學 100.00%
發明人	汪宏達,蕭詠駿,邱于庭,喻秋華
技術領域	生化醫藥

專利摘要(中)
Disclosed is a method for early diagnosis of liver cancer. The method comprises the steps of: (A) providing a sample obtained from a subject; (B) assessing the expression level of four subtypes of .alpha.-mannosidase genes consisting of MAN1C1 in the sample; (C) comparing the expression level of .alpha.-mannosidase genes in the sample with a normal control; and (D) determining whether the subject having a risk of suffering liver cancer in accordance with the result of step (C); wherein while the MAN1C1 expression level of the sample is lower than that in the normal control, the subject is determined to have a risk of suffering liver cancer. Additionally, while MAN1A1, MAN1A2 and MAN1B1 expression levels in the sample are higher than those in control group, the subject is determined to suffer from liver cancer and has a risk of metastasis.

專利摘要(中)

Disclosed is a method for early diagnosis of liver cancer. The method comprises the steps of: (A) providing a sample obtained from a subject; (B) assessing the expression level of four subtypes of .alpha.-mannosidase genes consisting of MAN1C1 in the sample; (C) comparing the expression level of .alpha.-mannosidase genes in the sample with a normal control; and (D) determining whether the subject having a risk of suffering liver cancer in accordance with the result of step (C); wherein while the MAN1C1 expression level of the sample is lower than that in the normal control, the subject is determined to have a risk of suffering liver cancer. Additionally, while MAN1A1, MAN1A2 and MAN1B1 expression levels in the sample are higher than those in control group, the subject is determined to suffer from liver cancer and has a risk of metastasis.

聯絡資訊
承辦人姓名	劉千綺
承辦人電話	03-571-5131 #31181
承辦人Email	chienchi@mx.nthu.edu.tw