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專利授權區
專利名稱(中)	收集類澱粉蛋白的系統、其用途及移除類澱粉蛋白的方法
專利名稱(英)	SYSTEM FOR COLLECTING AMYLOID, USE THEREOF, AND METHOD FOR REMOVING AMYLOID
專利家族	中華民國：I725702 美國：US-2021-0213052-A1(公開號)
專利權人	國立清華大學 100.00%
發明人	邱信程,蔡源鍾,駱敬謙,劉得懿,張琇涵
技術領域	材料化工,生化醫藥

專利摘要(中)
本發明提供一種收集類澱粉蛋白的系統包含一反應槽、至少一奈微米磁棒、一旋轉磁場供應裝置以及一驅動裝置。反應槽包含複數個吞噬細胞。旋轉磁場供應裝置用以提供一旋轉磁場至反應槽。當旋轉磁場供應裝置受驅動裝置驅動並於反應槽提供旋轉磁場時，奈微米磁棒將受旋轉磁場驅動而於反應槽中自轉，而反應槽中的樣本將對應奈微米磁棒的自轉而產生一微漩渦流以使類澱粉蛋白聚集，並在後續為吞噬細胞捕捉。藉此，本發明之收集類澱粉蛋白的系統可在不破壞樣本的前提下透過吞噬細胞溫和地移除與代謝其中的類澱粉蛋白，並具有相關市場的應用潛力。

專利摘要(中)

本發明提供一種收集類澱粉蛋白的系統包含一反應槽、至少一奈微米磁棒、一旋轉磁場供應裝置以及一驅動裝置。反應槽包含複數個吞噬細胞。旋轉磁場供應裝置用以提供一旋轉磁場至反應槽。當旋轉磁場供應裝置受驅動裝置驅動並於反應槽提供旋轉磁場時，奈微米磁棒將受旋轉磁場驅動而於反應槽中自轉，而反應槽中的樣本將對應奈微米磁棒的自轉而產生一微漩渦流以使類澱粉蛋白聚集，並在後續為吞噬細胞捕捉。藉此，本發明之收集類澱粉蛋白的系統可在不破壞樣本的前提下透過吞噬細胞溫和地移除與代謝其中的類澱粉蛋白，並具有相關市場的應用潛力。

專利摘要(英)
The present disclosure provides a system for collecting amyloid including a reaction tank, at least one nano-micro magnetic stir bar, a rotating magnetic field supply device and a driving device. The reaction tank includes a plurality of phagocytes. The rotating magnetic field supply device is used to provide a rotating magnetic field to the reaction tank. When the rotating magnetic field supply device is driven by the driving device and provides the rotating magnetic field to the reaction tank, the nano-micro magnetic stir bar will be driven by the rotating magnetic field so as to rotate in the reaction tank, and a micro-whirlpool flow of a sample in the reaction tank will be generated corresponding to the rotation of the nano-micro magnetic stir bar. Thus, the amyloid will be gathered and captured by the phagocytes later. Therefore, the system for collecting amyloid of the present disclosure can gently remove and metabolite the amyloid by the phagocytes without destroying the sample and can have potential to apply in the relevant market.

專利摘要(英)

The present disclosure provides a system for collecting amyloid including a reaction tank, at least one nano-micro magnetic stir bar, a rotating magnetic field supply device and a driving device. The reaction tank includes a plurality of phagocytes. The rotating magnetic field supply device is used to provide a rotating magnetic field to the reaction tank. When the rotating magnetic field supply device is driven by the driving device and provides the rotating magnetic field to the reaction tank, the nano-micro magnetic stir bar will be driven by the rotating magnetic field so as to rotate in the reaction tank, and a micro-whirlpool flow of a sample in the reaction tank will be generated corresponding to the rotation of the nano-micro magnetic stir bar. Thus, the amyloid will be gathered and captured by the phagocytes later. Therefore, the system for collecting amyloid of the present disclosure can gently remove and metabolite the amyloid by the phagocytes without destroying the sample and can have potential to apply in the relevant market.

聯絡資訊
承辦人姓名	楊美茹
承辦人電話	03-5715131 #62305
承辦人Email	mjyang2@mx.nthu.edu.tw