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專利授權區
專利名稱(中)	肺呼吸晶片與細胞拉伸培養平台及其運作方法
專利名稱(英)	LUNG BREATHING CHIP AND CELL STRETCHING CULTURE PLATFORM AND OPERATING METHOD THEREOF
專利家族	中華民國：I775554 大陸：CN 115703992 A(公開號) 美國：US-2023-0039490-A1(公開號)
專利權人	國立清華大學 50.00% ,臺北醫學大學 50.00%
發明人	劉承賢,黃丞佑,宋俊輝,賴品慈,許家銘,梁一穎,李岡遠,孫偉倫,何淑娟
技術領域	材料化工,生化醫藥,機械結構,電子電機

專利摘要(中)
本發明揭露一種肺呼吸晶片與細胞拉伸培養平台及其運作方法。肺呼吸晶片與細胞拉伸培養平台係透過程式編寫控制馬達輸出、利用凸輪元件對微流體晶片進行拉伸、改變凸輪元件的尺寸及馬達轉動的頻率來改變拉伸頻率及拉伸量，以模擬不同狀態下的肺部呼吸情況、透過液體介電泳技術對生物相容性水膠及水膠中的細胞進行三維排列，以仿造出三維的細胞組織、以及透過動態灌流系統灌流藥物，以實現晶片仿生肺組織中細胞受到拉伸時的藥物測試平台。

專利摘要(中)

本發明揭露一種肺呼吸晶片與細胞拉伸培養平台及其運作方法。肺呼吸晶片與細胞拉伸培養平台係透過程式編寫控制馬達輸出、利用凸輪元件對微流體晶片進行拉伸、改變凸輪元件的尺寸及馬達轉動的頻率來改變拉伸頻率及拉伸量，以模擬不同狀態下的肺部呼吸情況、透過液體介電泳技術對生物相容性水膠及水膠中的細胞進行三維排列，以仿造出三維的細胞組織、以及透過動態灌流系統灌流藥物，以實現晶片仿生肺組織中細胞受到拉伸時的藥物測試平台。

專利摘要(英)
A lung breathing chip and cell stretching culture platform and an operating method thereof are disclosed. The lung breathing chip and cell stretching culture platform controls the output of the motor by programming, stretches the micro-fluidic chip by the cam component, changes the size of the cam component and the frequency of the motor rotation to change the stretching frequency and the amount of stretching to simulate the breathing of the lungs in different states, uses liquid electrophoresis technology to arrange the cells in the biocompatible water gel and the water gel three-dimensionally to imitate the three-dimensional cell tissue, and injects drugs through the dynamic perfusion system to realize the drug testing platform that the cells of the chip bionic lung tissue are stretched.

專利摘要(英)

A lung breathing chip and cell stretching culture platform and an operating method thereof are disclosed. The lung breathing chip and cell stretching culture platform controls the output of the motor by programming, stretches the micro-fluidic chip by the cam component, changes the size of the cam component and the frequency of the motor rotation to change the stretching frequency and the amount of stretching to simulate the breathing of the lungs in different states, uses liquid electrophoresis technology to arrange the cells in the biocompatible water gel and the water gel three-dimensionally to imitate the three-dimensional cell tissue, and injects drugs through the dynamic perfusion system to realize the drug testing platform that the cells of the chip bionic lung tissue are stretched.

聯絡資訊
承辦人姓名	劉千綺
承辦人電話	03-571-5131 #31181
承辦人Email	chienchi@mx.nthu.edu.tw