| A drug screening platform for tumor microenvironment simulation includes a tumor microenvironment simulating chip, a drug testing chip, and a permeable thin film disposed between the tumor microenvironment simulating chip and the drug testing chip. The tumor microenvironment simulating chip includes a microenvironment building unit which is used for conducting a chemical reaction to generate an acid gas, an alkaline gas and/or an oxygen concentration for simulating the tumor microenvironment. The drug testing chip includes a testing unit which is used for allowing interaction of a therapeutic drug with a cell-containing hydrogel. An orthographic projection of the testing unit falls on the microenvironment building unit. The permeable thin film is used for diffusing the acid gas, the alkaline gas and/or the oxygen concentration generated by the microenvironment building unit to the testing unit. |