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專利授權區
專利名稱(中)	[123I]標記碘辛基芬布芬醯胺化合物之製備方法及其應用
專利名稱(英)	METHOD OF PREPARING [123I]IODOOCTYL FENBUFEN AMIDE AND APPLICATION THEREOF
專利家族	美國：8,986,652
專利權人	國立清華大學 100%
發明人	黃鶴聯,樊修秀,葉俊男,田書帆,楊慶鉉,張剛瑋,林昆儒,林武智,李維元,蘇文欽,黃盈誠,俞鐘山,陳振宗
技術領域	生化醫藥

專利摘要(中)
The present invention provides a method of preparing [.sup.123I]Iodooctyl fenbufen amide with a radiochemical yield of 15％, a specific activity of 37 GBq/.mu.mol and radiochemical purity of 95％. The present invention further provides a method of applying [.sup.123I]Iodooctyl fenbufen amide as tracer of single photon emission computer tomography (SPECT) to estimate the distribution of cyclooxygenase. By the binding characteristics of the iodine isotope-labeled compounds and the positive correlation of inflammation to tumor lesion, the present invention can estimate the tumor development and metastasis.

專利摘要(中)

The present invention provides a method of preparing [.sup.123I]Iodooctyl fenbufen amide with a radiochemical yield of 15％, a specific activity of 37 GBq/.mu.mol and radiochemical purity of 95％. The present invention further provides a method of applying [.sup.123I]Iodooctyl fenbufen amide as tracer of single photon emission computer tomography (SPECT) to estimate the distribution of cyclooxygenase. By the binding characteristics of the iodine isotope-labeled compounds and the positive correlation of inflammation to tumor lesion, the present invention can estimate the tumor development and metastasis.

聯絡資訊
承辦人姓名	鍾弦靜