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專利授權區
專利名稱(中) METHODS FOR DETECTING AND TREATING CHOLANGIOCARCINOMA
專利家族 中華民國:I778596
美國:US 11,506,664 B1
專利權人 中央研究院 51% ,國立清華大學 49%
發明人 李國賓,洪上程,普麗雅
技術領域 生化醫藥
專利摘要(中)
Disclosed herein is a novel compound of formula (I) for detecting circulating cancerous cells, particularly, cholangio-cancerous cells, from a biological sample,wherein, R1 and R2 are independently H, or –SO3M; and M is a monovalent cation selected from the group consisting of sodium ion, potassium ion, lithium ion or ammonium ion. Also disclosed herein is a method of detecting cholangio-cancerous cells from a biological sample of a subject suspected of having cholangiocarcinoma (CCA). The method includes steps of, contacting the biological sample with a magnetic bead pre-coated with the compound of formula (I); detecting a complex formed between the magnetic bead and the biological sample in an immunoassay; wherein, the presence of the complex is an indication that the subject has CCA.
聯絡資訊
承辦人姓名 劉千綺
承辦人電話 03-571-5131 #31181
承辦人Email chienchi@mx.nthu.edu.tw
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