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專利授權區
專利名稱(中)	對卵巢癌具有專一性之適合體及其應用
專利名稱(英)	Ovarian cancer-specific aptamers and applications thereof
專利家族	中華民國：I623617 美國：9,783,808
專利權人	國立清華大學 100%
發明人	洪廉育,王志宏,李國賓
技術領域	生化醫藥

專利摘要(中)
本發明提供一種對卵巢癌細胞具有專一性之適合體，其是由系統性配分子指數增益演繹程序(Systematic evolution of ligands by exponential enrichment，SELEX)與微流體晶片系統體外篩選而得。該些適合體更可分別結合不同組織學型態的卵巢癌細胞，且具有高結合率。因此本發明之適合體不僅可用於檢測卵巢癌細胞，亦可用於識別不同組織型態之卵巢癌細胞。 The present invention provides ovarian cancer-specific aptamers, which were selected in vitro using SELEX and a microfluidic chip system. The aptamers can also bind to different histologically-classified ovarian cancer cells with high affinity accordingly. Therefore, the aptamers of the present invention and the application thereof can not only be used in detection of ovarian cancer cells but also be applied in recognition of different histologically-classified ovarian cancer cells.

專利摘要(中)

本發明提供一種對卵巢癌細胞具有專一性之適合體，其是由系統性配分子指數增益演繹程序(Systematic evolution of ligands by exponential enrichment，SELEX)與微流體晶片系統體外篩選而得。該些適合體更可分別結合不同組織學型態的卵巢癌細胞，且具有高結合率。因此本發明之適合體不僅可用於檢測卵巢癌細胞，亦可用於識別不同組織型態之卵巢癌細胞。 The present invention provides ovarian cancer-specific aptamers, which were selected in vitro using SELEX and a microfluidic chip system. The aptamers can also bind to different histologically-classified ovarian cancer cells with high affinity accordingly. Therefore, the aptamers of the present invention and the application thereof can not only be used in detection of ovarian cancer cells but also be applied in recognition of different histologically-classified ovarian cancer cells.

聯絡資訊
承辦人姓名	劉千綺
承辦人電話	03-571-5131 #31181
承辦人Email	chienchi@mx.nthu.edu.tw